Jamming Resistant Receivers for Massive MIMO

We design jamming resistant receivers to enhance the robustness of a massive MIMO uplink channel against jamming. In the pilot phase, we estimate not only the desired channel, but also the jamming channel by exploiting purposely unused pilot sequences. The jamming channel estimate is used to construct the linear receive filter to reduce impact that jamming has on the achievable rates. The performance of the proposed scheme is analytically and numerically evaluated. These results show that the proposed scheme greatly improves the rates, as compared to conventional receivers. Moreover, the proposed schemes still work well with stronger jamming power.Comment: Accepted in the 42nd IEEE Int. Conf. Acoust., Speech, and Signal Process. (ICASSP2017

Statistical estimation of frictional coefficients of faults based on a structural dataset in the Tuy Hoa–Vung Tau Region, Viet Nam

This study estimates the shear friction coefficient from shear friction angles for the prediction of slip tendencies in the Tuy Hoa–Vung Tau region of Southern Vietnam. A dataset consisting of measured data of 355 fractured planes, striations, and unconformities in coastal areas as well as 239 offshore faults was analyzed based on the principles of statistical probability. As a result, 138 friction angles for the onshore and offshore faults were calculated based on shear fracture conjugate pairs. The goodness-of-fit test was used to define the probability distribution of the friction angles, which had a normal distribution. The acceptable average of friction angles for the onshore region with a reliability of more than 95% were in the range of 25.8–31.5°, which corresponds to frictional coefficients of 0.48–0.61. The acceptable average friction angles for the offshore region were relatively low at 23–31°, which corresponds to a frictional coefficient of 0.42–0.60. Owing to the heterogeneity of the fault system, the median value (19.12°) should be used as the lowest threshold value for slipping faults at all conditions. The recommended applicable average friction angles are 28.65° and 27° for the onshore and offshore regions, respectively. The estimation of the frictional coefficients is highly reliable, and it can be applied to other subsurface resource exploitation projects within the study area

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies PDGFRA as a Susceptibility Locus for Corneal Astigmatism

Corneal astigmatism refers to refractive abnormalities and irregularities in the curvature of the cornea, and this interferes with light being accurately focused at a single point in the eye. This ametropic condition is highly prevalent, influences visual acuity, and is a highly heritable trait. There is currently a paucity of research in the genetic etiology of corneal astigmatism. Here we report the results from five genome-wide association studies of corneal astigmatism across three Asian populations, with an initial discovery set of 4,254 Chinese and Malay individuals consisting of 2,249 cases and 2,005 controls. Replication was obtained from three surveys comprising of 2,139 Indians, an additional 929 Chinese children, and an independent 397 Chinese family trios. Variants in PDGFRA on chromosome 4q12 (lead SNP: rs7677751, allelic odds ratio = 1.26 (95% CI: 1.16–1.36), Pmeta = 7.87×10−9) were identified to be significantly associated with corneal astigmatism, exhibiting consistent effect sizes across all five cohorts. This highlights the potential role of variants in PDGFRA in the genetic etiology of corneal astigmatism across diverse Asian populations

A common variant near TGFBR3 is associated with primary open angle glaucoma

Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex disease with a significant genetic contribution. We performed Exome Array (Illumina) analysis on 3504 POAG cases and 9746 controls with replication of the most significant findings in 9173 POAG cases and 26 780 controls across 18 collections of Asian, African and European descent. Apart from confirming strong evidence of association at CDKN2B-AS1 (rs2157719 [G], odds ratio [OR] = 0.71, P = 2.81 × 10−33), we observed one SNP showing significant association to POAG (CDC7–TGFBR3 rs1192415, ORG-allele = 1.13, Pmeta = 1.60 × 10−8). This particular SNP has previously been shown to be strongly associated with optic disc area and vertical cup-to-disc ratio, which are regarded as glaucoma-related quantitative traits. Our study now extends this by directly implicating it in POAG disease pathogenesis